Do not take PAXLOVID™ if:
- You are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID™.
- You are taking any of the following medicines:
o Pethidine, piroxicam, propoxyphene
o Amiodarone, dronedarone, flecainide, propafenone, quinidine
o Lurasidone, pimozide, clozapine
o Dihydroergotamine, ergotamine, methylergonovine
o Lovastatin, simvastatin
o Sildenafil (Revatio®) for pulmonary arterial hypertension (PAH)
o Triazolam, oral midazolam
o Carbamazepine, phenobarbital, phenytoin
o St. John’s Wort (hypericum perforatum)
Taking PAXLOVID with these medicines may cause serious or life-threatening side
effects or affect how PAXLOVID works.
These are not the only medicines that may cause serious side effects if taken with
PAXLOVID™. PAXLOVID™ may increase or decrease the levels of multiple other
medicines. It is very important to tell your healthcare provider about all of the medicines
you are taking because additional laboratory tests or changes in the dose of your other
medicines may be necessary while you are taking PAXLOVID™. Your healthcare provider
may also tell you about specific symptoms to watch out for that may indicate that you
need to stop or decrease the dose of some of your other medicines.