Frequent diaper changes, especially when wet or soiled, gentle and thorough cleaning with mild products or soaps, and use of over-the-counter barrier products can prevent diaper rash. Many products are available at pharmacies, grocery stores, or online to prevent diaper rash. Products containing petrolatum, vitamins A&D, or zinc oxide work well to prevent and treat mild diaper rash. It’s best to avoid powders and products with additives or fragrances. Thoroughly and gently cleaning the diaper area with a washcloth and warm water can help to prevent diaper rash. You can also use a mild, unscented soap to clean off stool, but be sure no soap is left on the skin. Clean thoroughly in skin fold areas, including around the labia in girls and scrotum in boys. It can also help to leave the area exposed to air for periods of time. Avoid baby wipes that contain alcohol or scented products, including preservatives such as formaldehyde, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), which can cause skin irritation. Diapers that are too tight can also contribute to rash.