Take the medication on an empty stomach (60 minutes before breakfast or bedtime (3 or more hours after evening meal)
Take levothyroxine at least four hours before or after taking with other medications that are known to interact with levothyroxine such as calcium carbonate or iron sulfate and even antacid
Do not take the medication with food
Notify your provider if you start taking new medications, large changes in body weight, or if you become pregnant