The only way to avoid STIs is to not have vaginal, anal, or oral sex.
If you are sexually active, you can do the following things to lower your chances of getting syphilis:
- Be in a long-term mutually monogamous relationship with a partner who has been tested for syphilis and does not have syphilis;
- Use latex condoms the right way every time you have sex. Condoms prevent transmission of syphilis by preventing contact with a sore. Sometimes sores occur in areas not covered by a condom. Contact with these sores can still transmit syphilis.