Trichomoniasis is the most common non viral STI in the United States. Trichomoniasis is a condition caused by the microscopic parasite Trichomonas vaginalis. It is spread through sex. Infection is most common in females assigned at birth. Older people are more likely than younger people to have been infected with trichomoniasis. People who have trichomoniasis are at an increased risk of infection with other sexually transmitted infections (STIs).