What are the risks or side effects of taking Latisse? May 30, 2019 22:26 The most common side effects are itching sensation, skin darkening, eye irritation, dry eyes, and redness of the eyelids. Related articles Is Latisse effective? Is there an alternative to Latisse? How much does it cost to use Alpha? How to properly apply Latisse Can a doctor diagnose inadequate lashes remotely?