What are the risks or side effects of taking Latisse? May 30, 2019 22:26 The most common side effects are itching sensation, skin darkening, eye irritation, dry eyes, and redness of the eyelids. Related articles Is Latisse effective? Can a doctor diagnose inadequate lashes remotely? Is there an alternative to Latisse? How much does it cost to use Alpha? How does Latisse work?